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Oxidative stress promotes autophagic cell death in human neuroblastoma cells with ectopic transfer of mitochondrial PPP2R2B (Bβ2)

BACKGROUND: The multifunctional protein phosphatase 2A (PP2A) is a heterotrimeric serine/threonine protein phosphatase composed of a scaffolding, catalytic and regulatory subunits. By modifying various downstream signal transducers, the aberrant expression of the brain-targeted regulatory subunit PP...

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Detalles Bibliográficos
Autores principales: Cheng, Wan-Ting, Guo, Zhi-Xuan, Lin, Chia-An, Lin , Ming-Yi, Tung, Li-Chu, Fang, Kang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810296/
https://www.ncbi.nlm.nih.gov/pubmed/20017961
http://dx.doi.org/10.1186/1471-2121-10-91