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Restoration of contact inhibition in human glioblastoma cell lines after MIF knockdown

BACKGROUND: Studies of the role of the cytokine macrophage-migration-inhibitory-factor (MIF) in malignant tumors have revealed its stimulating influence on cell-cycle progression, angiogenesis and anti-apoptosis. RESULTS: Here we show that in vitro targeting MIF in cultures of human malignant gliobl...

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Detalles Bibliográficos
Autores principales: Schrader, Jörg, Deuster, Oliver, Rinn, Birgit, Schulz, Martina, Kautz, Andreas, Dodel, Richard, Meyer, Bernhard, Al-Abed, Yousef, Balakrishnan, Karthikeyan, Reese, Jens P, Bacher, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810303/
https://www.ncbi.nlm.nih.gov/pubmed/20038293
http://dx.doi.org/10.1186/1471-2407-9-464