RNA Microarray Analysis in Prenatal Mouse Cochlea Reveals Novel IGF-I Target Genes: Implication of MEF2 and FOXM1 Transcription Factors

BACKGROUND: Insulin-like growth factor-I (IGF-I) provides pivotal cell survival and differentiation signals during inner ear development throughout evolution. Homozygous mutations of human IGF1 cause syndromic sensorineural deafness, decreased intrauterine and postnatal growth rates, and mental reta...

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Detalles Bibliográficos
Autores principales: Sanchez-Calderon, Hortensia, Rodriguez-de la Rosa, Lourdes, Milo, Marta, Pichel, Jose G., Holley, Matthew, Varela-Nieto, Isabel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810322/
https://www.ncbi.nlm.nih.gov/pubmed/20111592
http://dx.doi.org/10.1371/journal.pone.0008699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810322/
https://www.ncbi.nlm.nih.gov/pubmed/20111592
http://dx.doi.org/10.1371/journal.pone.0008699

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