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Flavin Adenine Dinucleotide Rescues the Phenotype of Frataxin Deficiency
BACKGROUND: Friedreich ataxia is a neurodegenerative disease caused by the lack of frataxin, a mitochondrial protein. We previously demonstrated that frataxin interacts with complex II subunits of the electronic transport chain (ETC) and putative electronic transfer flavoproteins, suggesting that fr...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810331/ https://www.ncbi.nlm.nih.gov/pubmed/20111601 http://dx.doi.org/10.1371/journal.pone.0008872 |