Allosteric Regulation of HIV-1 Reverse Transcriptase by ATP for Nucleotide Selection

BACKGROUND: Human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) is a DNA polymerase that converts viral RNA genomes into proviral DNAs. How HIV-1 RT regulates nucleotide selectivity is a central issue for genetics and the nucleoside analog RT inhibitor (NRTI) resistance of HIV-1. ME...

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Detalles Bibliográficos
Autores principales: Yokoyama, Masaru, Mori, Hiromi, Sato, Hironori
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810339/
https://www.ncbi.nlm.nih.gov/pubmed/20111609
http://dx.doi.org/10.1371/journal.pone.0008867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810339/
https://www.ncbi.nlm.nih.gov/pubmed/20111609
http://dx.doi.org/10.1371/journal.pone.0008867

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