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Allosteric Regulation of HIV-1 Reverse Transcriptase by ATP for Nucleotide Selection

BACKGROUND: Human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) is a DNA polymerase that converts viral RNA genomes into proviral DNAs. How HIV-1 RT regulates nucleotide selectivity is a central issue for genetics and the nucleoside analog RT inhibitor (NRTI) resistance of HIV-1. ME...

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Detalles Bibliográficos
Autores principales:	Yokoyama, Masaru, Mori, Hiromi, Sato, Hironori
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810339/ https://www.ncbi.nlm.nih.gov/pubmed/20111609 http://dx.doi.org/10.1371/journal.pone.0008867

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