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Nucleolar retention of a translational C/EBPα isoform stimulates rDNA transcription and cell size

The messenger RNA of the intronless CEBPA gene is translated into distinct protein isoforms through the usage of consecutive translation initiation sites. These translational isoforms have distinct functions in the regulation of differentiation and proliferation due to the presence of different N-te...

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Detalles Bibliográficos
Autores principales: Müller, Christine, Bremer, Anna, Schreiber, Sandra, Eichwald, Sabrina, Calkhoven, Cornelis F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810377/
https://www.ncbi.nlm.nih.gov/pubmed/20075868
http://dx.doi.org/10.1038/emboj.2009.404