Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice

Recombinant severe acute respiratory virus (SARS-CoV) variants lacking the group specific genes 6, 7a, 7b, 8a, 8b and 9b (rSARS-CoV-Δ[6–9b]), the structural gene E (rSARS-CoV-ΔE), and a combination of both sets of genes (rSARS-CoV-Δ[E,6–9b]) have been generated. All these viruses were rescued in mon...

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Detalles Bibliográficos
Autores principales: DeDiego, Marta L., Pewe, Lecia, Alvarez, Enrique, Rejas, Maria Teresa, Perlman, Stanley, Enjuanes, Luis
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810402/
https://www.ncbi.nlm.nih.gov/pubmed/18452964
http://dx.doi.org/10.1016/j.virol.2008.03.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810402/
https://www.ncbi.nlm.nih.gov/pubmed/18452964
http://dx.doi.org/10.1016/j.virol.2008.03.005

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