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A profusion of upstream open reading frame mechanisms in polyamine-responsive translational regulation

In many eukaryotic mRNAs one or more short ‘upstream’ open reading frames, uORFs, precede the initiator of the main coding sequence. Upstream ORFs are functionally diverse as illustrated by their variety of features in polyamine pathway biosynthetic mRNAs. Their propensity to act as sensors for regu...

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Detalles Bibliográficos
Autores principales: Ivanov, Ivaylo P., Atkins, John F., Michael, Antony J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811004/
https://www.ncbi.nlm.nih.gov/pubmed/19920120
http://dx.doi.org/10.1093/nar/gkp1037