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Functional properties and evolutionary splicing constraints on a composite exonic regulatory element of splicing in CFTR exon 12

In general, splicing regulatory elements are defined as Enhancers or Silencers depending on their positive or negative effect upon exon inclusion. Often, these sequences are usually present separate from each other in exonic/intronic sequences. The Composite Exonic Splicing Regulatory Elements (CERE...

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Detalles Bibliográficos
Autores principales: Haque, Ariful, Buratti, Emanuele, Baralle, Francisco E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811005/
https://www.ncbi.nlm.nih.gov/pubmed/19910374
http://dx.doi.org/10.1093/nar/gkp1040