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The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis
The repair of DNA double-strand breaks (DSBs) is essential to maintain genomic integrity. In higher eukaryotes, DNA DSBs are predominantly repaired by non-homologous end joining (NHEJ), but DNA ends can also be joined by an alternative error-prone mechanism termed microhomology-mediated end joining...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811014/ https://www.ncbi.nlm.nih.gov/pubmed/19892829 http://dx.doi.org/10.1093/nar/gkp905 |