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The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis

The repair of DNA double-strand breaks (DSBs) is essential to maintain genomic integrity. In higher eukaryotes, DNA DSBs are predominantly repaired by non-homologous end joining (NHEJ), but DNA ends can also be joined by an alternative error-prone mechanism termed microhomology-mediated end joining...

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Detalles Bibliográficos
Autores principales:	Taylor, Elaine M., Cecillon, Sophie M., Bonis, Antonio, Chapman, J. Ross, Povirk, Lawrence F., Lindsay, Howard D.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811014/ https://www.ncbi.nlm.nih.gov/pubmed/19892829 http://dx.doi.org/10.1093/nar/gkp905

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