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Optimizing nucleotide sequence ensembles for combinatorial protein libraries using a genetic algorithm
Protein libraries are essential to the field of protein engineering. Increasingly, probabilistic protein design is being used to synthesize combinatorial protein libraries, which allow the protein engineer to explore a vast space of amino acid sequences, while at the same time placing restrictions o...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811015/ https://www.ncbi.nlm.nih.gov/pubmed/19889723 http://dx.doi.org/10.1093/nar/gkp906 |