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Reconstructing nonlinear dynamic models of gene regulation using stochastic sampling

BACKGROUND: The reconstruction of gene regulatory networks from time series gene expression data is one of the most difficult problems in systems biology. This is due to several reasons, among them the combinatorial explosion of possible network topologies, limited information content of the experim...

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Detalles Bibliográficos
Autores principales: Mazur, Johanna, Ritter, Daniel, Reinelt, Gerhard, Kaderali, Lars
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811124/
https://www.ncbi.nlm.nih.gov/pubmed/20038296
http://dx.doi.org/10.1186/1471-2105-10-448