Cargando…
Global Regulator SATB1 Recruits β-Catenin and Regulates T(H)2 Differentiation in Wnt-Dependent Manner
In vertebrates, the conserved Wnt signalling cascade promotes the stabilization and nuclear accumulation of β-catenin, which then associates with the lymphoid enhancer factor/T cell factor proteins (LEF/TCFs) to activate target genes. Wnt/β -catenin signalling is essential for T cell development and...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811152/ https://www.ncbi.nlm.nih.gov/pubmed/20126258 http://dx.doi.org/10.1371/journal.pbio.1000296 |