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Global Regulator SATB1 Recruits β-Catenin and Regulates T(H)2 Differentiation in Wnt-Dependent Manner
In vertebrates, the conserved Wnt signalling cascade promotes the stabilization and nuclear accumulation of β-catenin, which then associates with the lymphoid enhancer factor/T cell factor proteins (LEF/TCFs) to activate target genes. Wnt/β -catenin signalling is essential for T cell development and...
Autores principales: | Notani, Dimple, Gottimukkala, Kamalvishnu P., Jayani, Ranveer S., Limaye, Amita S., Damle, Madhujit V., Mehta, Sameet, Purbey, Prabhat Kumar, Joseph, Jomon, Galande, Sanjeev |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811152/ https://www.ncbi.nlm.nih.gov/pubmed/20126258 http://dx.doi.org/10.1371/journal.pbio.1000296 |
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