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An Inhibitory Role of the G-Protein Regulator AGS3 in mTOR-Dependent Macroautophagy

Macroautophagy is a cellular process whereby the cell sequesters and recycles cytosolic constituents in a lysosome-dependent manner. It has also been implicated in a number of disorders, including cancer and neurodegeneration. Although a previous report that AGS3 over-expression promotes macroautoph...

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Detalles Bibliográficos
Autores principales: Groves, Benjamin, Abrahamsen, Hilde, Clingan, Heather, Frantz, Michael, Mavor, Lauren, Bailey, Jeffrey, Ma, Dzwokai
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811177/
https://www.ncbi.nlm.nih.gov/pubmed/20126274
http://dx.doi.org/10.1371/journal.pone.0008877