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Improved Reconstruction of In Silico Gene Regulatory Networks by Integrating Knockout and Perturbation Data
We performed computational reconstruction of the in silico gene regulatory networks in the DREAM3 Challenges. Our task was to learn the networks from two types of data, namely gene expression profiles in deletion strains (the ‘deletion data’) and time series trajectories of gene expression after som...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811182/ https://www.ncbi.nlm.nih.gov/pubmed/20126643 http://dx.doi.org/10.1371/journal.pone.0008121 |