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Roles of the Src Tyrosine Kinases Lck and Fyn in Regulating γδTCR Signal Strength

Lck and Fyn, members of the Src family of tyrosine kinases, are key components of the αβTCR-coupled signaling pathway. While it is generally accepted that both Lck and Fyn positively regulate signal transduction by the αβTCR, recent studies have shown that Lck and Fyn have distinct functions in this...

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Detalles Bibliográficos
Autores principales: Laird, Renee M., Hayes, Sandra M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811189/
https://www.ncbi.nlm.nih.gov/pubmed/20126650
http://dx.doi.org/10.1371/journal.pone.0008899