In vitro synthesis of heparosan using recombinant Pasteurella multocida heparosan synthase PmHS2

In vertebrates and bacteria, heparosan the precursor of heparin is synthesized by glycosyltransferases via the stepwise addition of UDP-N-acetylglucosamine and UDP-glucuronic acid. As heparin-like molecules represent a great interest in the pharmaceutical area, the cryptic Pasteurella multocida hepa...

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Detalles Bibliográficos
Autores principales: Chavaroche, Anaïs A. E., Springer, Jan, Kooy, Floor, Boeriu, Carmen, Eggink, Gerrit
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Biotechnologically Relevant Enzymes and Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811250/
https://www.ncbi.nlm.nih.gov/pubmed/19756580
http://dx.doi.org/10.1007/s00253-009-2214-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811250/
https://www.ncbi.nlm.nih.gov/pubmed/19756580
http://dx.doi.org/10.1007/s00253-009-2214-2

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