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In vitro synthesis of heparosan using recombinant Pasteurella multocida heparosan synthase PmHS2

In vertebrates and bacteria, heparosan the precursor of heparin is synthesized by glycosyltransferases via the stepwise addition of UDP-N-acetylglucosamine and UDP-glucuronic acid. As heparin-like molecules represent a great interest in the pharmaceutical area, the cryptic Pasteurella multocida hepa...

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Detalles Bibliográficos
Autores principales:	Chavaroche, Anaïs A. E., Springer, Jan, Kooy, Floor, Boeriu, Carmen, Eggink, Gerrit
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2009
Materias:	Biotechnologically Relevant Enzymes and Proteins
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811250/ https://www.ncbi.nlm.nih.gov/pubmed/19756580 http://dx.doi.org/10.1007/s00253-009-2214-2

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