Aminoguanidine inhibits aortic hydrogen peroxide production, VSMC NOX activity and hypercontractility in diabetic mice

BACKGROUND: Dysfunctionally uncoupled endothelial nitric oxide synthase (eNOS) is involved in producing reactive oxygen species (ROS) in the diabetic endothelium. The present study investigated whether anti-diabetes drug Aminoguanidine (AG) has any effect on eNOS function and vascular oxidant stress...

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Detalles Bibliográficos
Autores principales: Oak, Jeong-Ho, Youn, Ji-Youn, Cai, Hua
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Original investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811700/
https://www.ncbi.nlm.nih.gov/pubmed/20040119
http://dx.doi.org/10.1186/1475-2840-8-65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811700/
https://www.ncbi.nlm.nih.gov/pubmed/20040119
http://dx.doi.org/10.1186/1475-2840-8-65

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