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A Photoprotein in Mouse Embryonic Stem Cells Measures Ca(2+) Mobilization in Cells and in Animals
Exogenous expression of pharmacological targets in transformed cell lines has been the traditional platform for high throughput screening of small molecules. However, exogenous expression in these cells is limited by aberrant dosage, or its toxicity, the potential lack of interaction partners, and a...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811732/ https://www.ncbi.nlm.nih.gov/pubmed/20111708 http://dx.doi.org/10.1371/journal.pone.0008882 |