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A Photoprotein in Mouse Embryonic Stem Cells Measures Ca(2+) Mobilization in Cells and in Animals

Exogenous expression of pharmacological targets in transformed cell lines has been the traditional platform for high throughput screening of small molecules. However, exogenous expression in these cells is limited by aberrant dosage, or its toxicity, the potential lack of interaction partners, and a...

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Detalles Bibliográficos
Autores principales: Cainarca, Silvia, Fenu, Simone, Ferri, Cinzia, Nucci, Cinzia, Arioli, Patrizia, Menegon, Andrea, Piemonti, Lorenzo, Lohmer, Stefan, Wrabetz, Lawrence, Corazza, Sabrina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811732/
https://www.ncbi.nlm.nih.gov/pubmed/20111708
http://dx.doi.org/10.1371/journal.pone.0008882