Analysis of Compound Synergy in High-Throughput Cellular Screens by Population-Based Lifetime Modeling

Despite the successful introduction of potent anti-cancer therapeutics, most of these drugs lead to only modest tumor-shrinkage or transient responses, followed by re-growth of tumors. Combining different compounds has resulted in enhanced tumor control and prolonged survival. However, methods query...

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Detalles Bibliográficos
Autores principales: Peifer, Martin, Weiss, Jonathan, Sos, Martin L., Koker, Mirjam, Heynck, Stefanie, Netzer, Christian, Fischer, Stefanie, Rode, Haridas, Rauh, Daniel, Rahnenführer, Jörg, Thomas, Roman K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811738/
https://www.ncbi.nlm.nih.gov/pubmed/20111714
http://dx.doi.org/10.1371/journal.pone.0008919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811738/
https://www.ncbi.nlm.nih.gov/pubmed/20111714
http://dx.doi.org/10.1371/journal.pone.0008919

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