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Analysis of Compound Synergy in High-Throughput Cellular Screens by Population-Based Lifetime Modeling
Despite the successful introduction of potent anti-cancer therapeutics, most of these drugs lead to only modest tumor-shrinkage or transient responses, followed by re-growth of tumors. Combining different compounds has resulted in enhanced tumor control and prolonged survival. However, methods query...
Autores principales: | Peifer, Martin, Weiss, Jonathan, Sos, Martin L., Koker, Mirjam, Heynck, Stefanie, Netzer, Christian, Fischer, Stefanie, Rode, Haridas, Rauh, Daniel, Rahnenführer, Jörg, Thomas, Roman K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811738/ https://www.ncbi.nlm.nih.gov/pubmed/20111714 http://dx.doi.org/10.1371/journal.pone.0008919 |
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