The Zinc-Fingers of KREPA3 Are Essential for the Complete Editing of Mitochondrial mRNAs in Trypanosoma brucei

Most mitochondrial mRNAs in trypanosomes undergo uridine insertion/deletion editing that is catalyzed by ∼20S editosomes. The editosome component KREPA3 is essential for editosome structural integrity and its two zinc finger (ZF) motifs are essential for editing in vivo but not in vitro. KREPA3 func...

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Detalles Bibliográficos
Autores principales: Guo, Xuemin, Ernst, Nancy Lewis, Carnes, Jason, Stuart, Kenneth D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811742/
https://www.ncbi.nlm.nih.gov/pubmed/20111718
http://dx.doi.org/10.1371/journal.pone.0008913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811742/
https://www.ncbi.nlm.nih.gov/pubmed/20111718
http://dx.doi.org/10.1371/journal.pone.0008913

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