Pharmacokinetics and lung delivery of PDDS-aerosolized amikacin (NKTR-061) in intubated and mechanically ventilated patients with nosocomial pneumonia

INTRODUCTION: Aminoglycosides aerosolization might achieve better diffusion into the alveolar compartment than intravenous use. The objective of this multicenter study was to evaluate aerosol-delivered amikacin penetration into the alveolar epithelial lining fluid (ELF) using a new vibrating mesh ne...

Descripción completa

Detalles Bibliográficos
Autores principales: Luyt, Charles-Edouard, Clavel, Marc, Guntupalli, Kalpalatha, Johannigman, Jay, Kennedy, John I, Wood, Christopher, Corkery, Kevin, Gribben, Dennis, Chastre, Jean
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811890/
https://www.ncbi.nlm.nih.gov/pubmed/20003269
http://dx.doi.org/10.1186/cc8206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811890/
https://www.ncbi.nlm.nih.gov/pubmed/20003269
http://dx.doi.org/10.1186/cc8206

Ejemplares similares