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Pharmacokinetics and lung delivery of PDDS-aerosolized amikacin (NKTR-061) in intubated and mechanically ventilated patients with nosocomial pneumonia

INTRODUCTION: Aminoglycosides aerosolization might achieve better diffusion into the alveolar compartment than intravenous use. The objective of this multicenter study was to evaluate aerosol-delivered amikacin penetration into the alveolar epithelial lining fluid (ELF) using a new vibrating mesh ne...

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Detalles Bibliográficos
Autores principales:	Luyt, Charles-Edouard, Clavel, Marc, Guntupalli, Kalpalatha, Johannigman, Jay, Kennedy, John I, Wood, Christopher, Corkery, Kevin, Gribben, Dennis, Chastre, Jean
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811890/ https://www.ncbi.nlm.nih.gov/pubmed/20003269 http://dx.doi.org/10.1186/cc8206

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