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Kinetics of M(1) muscarinic receptor and G protein signaling to phospholipase C in living cells
G protein–coupled receptors (GPCRs) mediate responses to external stimuli in various cell types. Early events, such as the binding of ligand and G proteins to the receptor, nucleotide exchange (NX), and GTPase activity at the Gα subunit, are common for many different GPCRs. For G(q)-coupled M(1) mus...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812500/ https://www.ncbi.nlm.nih.gov/pubmed/20100890 http://dx.doi.org/10.1085/jgp.200910344 |