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Kinetics of PIP(2) metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells
The signaling phosphoinositide phosphatidylinositol 4,5-bisphosphate (PIP(2)) is synthesized in two steps from phosphatidylinositol by lipid kinases. It then interacts with KCNQ channels and with pleckstrin homology (PH) domains among many other physiological protein targets. We measured and develop...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812502/ https://www.ncbi.nlm.nih.gov/pubmed/20100891 http://dx.doi.org/10.1085/jgp.200910345 |