Pincher-generated Nogo-A endosomes mediate growth cone collapse and retrograde signaling

Nogo-A is one of the most potent myelin-associated inhibitors for axonal growth, regeneration, and plasticity in the adult central nervous system. The Nogo-A–specific fragment NogoΔ20 induces growth cone collapse, and inhibits neurite outgrowth and cell spreading by activating RhoA. Here, we show th...

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Detalles Bibliográficos
Autores principales: Joset, Armela, Dodd, Dana A., Halegoua, Simon, Schwab, Martin E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812518/
https://www.ncbi.nlm.nih.gov/pubmed/20083601
http://dx.doi.org/10.1083/jcb.200906089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812518/
https://www.ncbi.nlm.nih.gov/pubmed/20083601
http://dx.doi.org/10.1083/jcb.200906089

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