Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-L(S) substrates

Sophisticated quality control mechanisms prolong retention of protein-folding intermediates in the endoplasmic reticulum (ER) until maturation while sorting out terminally misfolded polypeptides for ER-associated degradation (ERAD). The presence of structural lesions in the luminal, transmembrane, o...

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Detalles Bibliográficos
Autores principales: Bernasconi, Riccardo, Galli, Carmela, Calanca, Verena, Nakajima, Toshihiro, Molinari, Maurizio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812524/
https://www.ncbi.nlm.nih.gov/pubmed/20100910
http://dx.doi.org/10.1083/jcb.200910042

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