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Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis

Members of the transforming growth factor β (TGF-β) family have been genetically linked to vascular formation during embryogenesis. However, contradictory studies about the role of TGF-β and other family members with reported vascular functions, such as bone morphogenetic protein (BMP) 9, in physiol...

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Detalles Bibliográficos
Autores principales: Cunha, Sara I., Pardali, Evangelia, Thorikay, Midory, Anderberg, Charlotte, Hawinkels, Lukas, Goumans, Marie-José, Seehra, Jasbir, Heldin, Carl-Henrik, ten Dijke, Peter, Pietras, Kristian
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812548/
https://www.ncbi.nlm.nih.gov/pubmed/20065063
http://dx.doi.org/10.1084/jem.20091309