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Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis
Members of the transforming growth factor β (TGF-β) family have been genetically linked to vascular formation during embryogenesis. However, contradictory studies about the role of TGF-β and other family members with reported vascular functions, such as bone morphogenetic protein (BMP) 9, in physiol...
Autores principales: | Cunha, Sara I., Pardali, Evangelia, Thorikay, Midory, Anderberg, Charlotte, Hawinkels, Lukas, Goumans, Marie-José, Seehra, Jasbir, Heldin, Carl-Henrik, ten Dijke, Peter, Pietras, Kristian |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812548/ https://www.ncbi.nlm.nih.gov/pubmed/20065063 http://dx.doi.org/10.1084/jem.20091309 |
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