Cargando…
Generation of PLZF(+) CD4(+) T cells via MHC class II–dependent thymocyte–thymocyte interaction is a physiological process in humans
Human thymocytes, unlike mouse thymocytes, express major histocompatibility complex (MHC) class II molecules on their surface, especially during the fetal and perinatal stages. Based on this observation, we previously identified a novel developmental pathway for the generation of CD4(+) T cells via...
Autores principales: | , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812550/ https://www.ncbi.nlm.nih.gov/pubmed/20038602 http://dx.doi.org/10.1084/jem.20091519 |