CD8(+) T cell concentration determines their efficiency in killing cognate antigen–expressing syngeneic mammalian cells in vitro and in mouse tissues

We describe a quantitative model for assessing the cytolytic activity of antigen-specific CD8(+) T cells in vitro and in vivo in which the concentration of antigen-specific CD8(+) T cells determines the efficiency with which these cells kill cognate antigen–expressing melanoma cells in packed cell p...

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Detalles Bibliográficos
Autores principales: Budhu, Sadna, Loike, John D., Pandolfi, Ashley, Han, Soo, Catalano, Geoffrey, Constantinescu, Andrei, Clynes, Raphael, Silverstein, Samuel C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812553/
https://www.ncbi.nlm.nih.gov/pubmed/20065066
http://dx.doi.org/10.1084/jem.20091279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812553/
https://www.ncbi.nlm.nih.gov/pubmed/20065066
http://dx.doi.org/10.1084/jem.20091279

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