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CD8(+) T cell concentration determines their efficiency in killing cognate antigen–expressing syngeneic mammalian cells in vitro and in mouse tissues
We describe a quantitative model for assessing the cytolytic activity of antigen-specific CD8(+) T cells in vitro and in vivo in which the concentration of antigen-specific CD8(+) T cells determines the efficiency with which these cells kill cognate antigen–expressing melanoma cells in packed cell p...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812553/ https://www.ncbi.nlm.nih.gov/pubmed/20065066 http://dx.doi.org/10.1084/jem.20091279 |