Cargando…

Fungal echinocandin resistance

The echinocandins are the newest class of antifungal agents in the clinical armory. These secondary metabolites are non-competitive inhibitors of the synthesis of β-(1,3)-glucan, a major structural component of the fungal cell wall. Recent work has shown that spontaneous mutations can arise in two h...

Descripción completa

Detalles Bibliográficos
Autores principales: Walker, Louise A., Gow, Neil A.R., Munro, Carol A.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812698/
https://www.ncbi.nlm.nih.gov/pubmed/19770064
http://dx.doi.org/10.1016/j.fgb.2009.09.003