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Characterization of a novel focal adhesion kinase inhibitor in human platelets

Focal adhesion kinase (FAK) is activated in human platelets downstream of integrins, e.g. α(IIb)β(3), and other adhesion receptors e.g. GPVI. Mice in which platelets lack FAK have been shown to exhibit extended bleeding times and their platelets have been shown to display decreased spreading on fibr...

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Detalles Bibliográficos
Autores principales: Jones, Matthew L., Shawe-Taylor, Amelia J., Williams, Christopher M., Poole, Alastair W.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812699/
https://www.ncbi.nlm.nih.gov/pubmed/19716803
http://dx.doi.org/10.1016/j.bbrc.2009.08.132