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Activation of Cdc6 by MyoD is associated with the expansion of quiescent myogenic satellite cells

MyoD is a transcriptional factor that is required for the differentiation of muscle stem cells (satellite cells). In this study, we describe a previously unknown function for MyoD in regulating a gene (Cdc6) that is vital to endowing chromatin with the capability of replicating DNA. In C2C12 and pri...

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Detalles Bibliográficos
Autores principales: Zhang, Keman, Sha, Jingfeng, Harter, Marian L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812847/
https://www.ncbi.nlm.nih.gov/pubmed/20048262
http://dx.doi.org/10.1083/jcb.200904144