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Recreation of the terminal events in physiological integrin activation

Increased affinity of integrins for the extracellular matrix (activation) regulates cell adhesion and migration, extracellular matrix assembly, and mechanotransduction. Major uncertainties concern the sufficiency of talin for activation, whether conformational change without clustering leads to acti...

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Detalles Bibliográficos
Autores principales: Ye, Feng, Hu, Guiqing, Taylor, Dianne, Ratnikov, Boris, Bobkov, Andrey A., McLean, Mark A., Sligar, Stephen G., Taylor, Kenneth A., Ginsberg, Mark H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812850/
https://www.ncbi.nlm.nih.gov/pubmed/20048261
http://dx.doi.org/10.1083/jcb.200908045