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Recreation of the terminal events in physiological integrin activation
Increased affinity of integrins for the extracellular matrix (activation) regulates cell adhesion and migration, extracellular matrix assembly, and mechanotransduction. Major uncertainties concern the sufficiency of talin for activation, whether conformational change without clustering leads to acti...
Autores principales: | Ye, Feng, Hu, Guiqing, Taylor, Dianne, Ratnikov, Boris, Bobkov, Andrey A., McLean, Mark A., Sligar, Stephen G., Taylor, Kenneth A., Ginsberg, Mark H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812850/ https://www.ncbi.nlm.nih.gov/pubmed/20048261 http://dx.doi.org/10.1083/jcb.200908045 |
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