Prometaphase spindle maintenance by an antagonistic motor-dependent force balance made robust by a disassembling lamin-B envelope

We tested the classical hypothesis that astral, prometaphase bipolar mitotic spindles are maintained by balanced outward and inward forces exerted on spindle poles by kinesin-5 and -14 using modeling of in vitro and in vivo data from Drosophila melanogaster embryos. Throughout prometaphase, puncta o...

Descripción completa

Detalles Bibliográficos
Autores principales: Civelekoglu-Scholey, Gul, Tao, Li, Brust-Mascher, Ingrid, Wollman, Roy, Scholey, Jonathan M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812851/
https://www.ncbi.nlm.nih.gov/pubmed/20065089
http://dx.doi.org/10.1083/jcb.200908150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812851/
https://www.ncbi.nlm.nih.gov/pubmed/20065089
http://dx.doi.org/10.1083/jcb.200908150

Ejemplares similares