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The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step

Clathrin heavy chain 22 (CHC22) is an isoform of the well-characterized CHC17 clathrin heavy chain, a coat component of vesicles that mediate endocytosis and organelle biogenesis. CHC22 has a distinct role from CHC17 in trafficking glucose transporter 4 (GLUT4) in skeletal muscle and fat, though its...

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Detalles Bibliográficos
Autores principales: Esk, Christopher, Chen, Chih-Ying, Johannes, Ludger, Brodsky, Frances M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812854/
https://www.ncbi.nlm.nih.gov/pubmed/20065094
http://dx.doi.org/10.1083/jcb.200908057