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Correlating measurements across samples improves accuracy of large-scale expression profile experiments

Gene expression profiling technologies suffer from poor reproducibility across replicate experiments. However, when analyzing large datasets, probe-level expression profile correlation can help identify flawed probes and lead to the construction of truer probe sets with improved reproducibility. We...

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Detalles Bibliográficos
Autores principales: Alvarez, Mariano Javier, Sumazin, Pavel, Rajbhandari, Presha, Califano, Andrea
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812950/
https://www.ncbi.nlm.nih.gov/pubmed/20042104
http://dx.doi.org/10.1186/gb-2009-10-12-r143