Functional Characterization of Transcription Factor Motifs Using Cross-species Comparison across Large Evolutionary Distances

We address the problem of finding statistically significant associations between cis-regulatory motifs and functional gene sets, in order to understand the biological roles of transcription factors. We develop a computational framework for this task, whose features include a new statistical score fo...

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Detalles Bibliográficos
Autores principales: Kim, Jaebum, Cunningham, Ryan, James, Brian, Wyder, Stefan, Gibson, Joshua D., Niehuis, Oliver, Zdobnov, Evgeny M., Robertson, Hugh M., Robinson, Gene E., Werren, John H., Sinha, Saurabh
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813253/
https://www.ncbi.nlm.nih.gov/pubmed/20126523
http://dx.doi.org/10.1371/journal.pcbi.1000652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813253/
https://www.ncbi.nlm.nih.gov/pubmed/20126523
http://dx.doi.org/10.1371/journal.pcbi.1000652

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