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Functional Characterization of Transcription Factor Motifs Using Cross-species Comparison across Large Evolutionary Distances
We address the problem of finding statistically significant associations between cis-regulatory motifs and functional gene sets, in order to understand the biological roles of transcription factors. We develop a computational framework for this task, whose features include a new statistical score fo...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813253/ https://www.ncbi.nlm.nih.gov/pubmed/20126523 http://dx.doi.org/10.1371/journal.pcbi.1000652 |