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Genetic Crossovers Are Predicted Accurately by the Computed Human Recombination Map

Hotspots of meiotic recombination can change rapidly over time. This instability and the reported high level of inter-individual variation in meiotic recombination puts in question the accuracy of the calculated hotspot map, which is based on the summation of past genetic crossovers. To estimate the...

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Detalles Bibliográficos
Autores principales: Khil, Pavel P., Camerini-Otero, R. Daniel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813264/
https://www.ncbi.nlm.nih.gov/pubmed/20126534
http://dx.doi.org/10.1371/journal.pgen.1000831