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Parasite-Derived Plasma Microparticles Contribute Significantly to Malaria Infection-Induced Inflammation through Potent Macrophage Stimulation

There is considerable debate as to the nature of the primary parasite-derived moieties that activate innate pro-inflammatory responses during malaria infection. Microparticles (MPs), which are produced by numerous cell types following vesiculation of the cellular membrane as a consequence of cell de...

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Detalles Bibliográficos
Autores principales: Couper, Kevin N., Barnes, Tom, Hafalla, Julius C. R., Combes, Valery, Ryffel, Bernhard, Secher, Thomas, Grau, Georges E., Riley, Eleanor M., de Souza, J. Brian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813278/
https://www.ncbi.nlm.nih.gov/pubmed/20126448
http://dx.doi.org/10.1371/journal.ppat.1000744