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Cytomegalovirus-Specific T Cells Persist at Very High Levels during Long-Term Antiretroviral Treatment of HIV Disease

BACKGROUND: In healthy, HIV seronegative, CMV seropositive adults, a large proportion of T cells are CMV-specific. High-level CMV-specific T cell responses are associated with accelerated immunologic aging (“immunosenesence”) in the elderly population. The impact of untreated and treated HIV infecti...

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Detalles Bibliográficos
Autores principales: Naeger, David M., Martin, Jeffrey N., Sinclair, Elizabeth, Hunt, Peter W., Bangsberg, David R., Hecht, Frederick, Hsue, Priscilla, McCune, Joseph M., Deeks, Steven G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813282/
https://www.ncbi.nlm.nih.gov/pubmed/20126452
http://dx.doi.org/10.1371/journal.pone.0008886